Peptide Playbook

Mood, Brain & Cognitive Support

Restore Mental Clarity, Motivation & Emotional Balance

Many patients don’t describe themselves as “depressed”—but they do feel foggy, unfocused, unmotivated, or emotionally depleted. Whether it’s due to stress, hormones, burnout, or chronic inflammation, this peptide stack supports neurological balance, mitochondrial energy, and emotional resilience without relying on antidepressants or stimulants.

This protocol is ideal for midlife patients, professionals under chronic stress, post-COVID recovery, and those who feel mentally “off” but show no clear lab abnormality.

Ideal Use Cases

Use this stack for patients who report:

  • Brain fog or forgetfulness
  • Low motivation, mood swings, or emotional flatness
  • Difficulty focusing or staying on task
  • Fatigue that’s mental, not just physical
  • Anxiety or restlessness that seems hormonal or stress-driven
  • Lack of libido or emotional connection

Best for:

  • Perimenopausal and postmenopausal women
  • High-stress professionals or entrepreneurs
  • GLP-1 patients with fatigue or mood flattening
  • Patients recovering from illness, inflammation, or burnout

ShineRx Core Compounds for Mood & Focus

CompoundFunctionNotes
NAD+Supports brain cell energy, focus, neuroprotectionEssential for cognition, stress tolerance, and executive function
SermorelinImproves deep sleep and growth hormone balanceBetter sleep = improved mood and cognitive regulation
MIC/B6/B12Supports methylation and neurotransmitter balanceWeekly boost for focus, energy, and clarity
PeptideViteFoundational micronutrient supportHelps normalize brain chemistry and mitochondrial health
L-CarnitineImproves brain energy, memory, and mitochondrial outputOptional add-on for mental fatigue or ADHD-adjacent symptoms

Optional additions:

  • PT-141 (when mood issues are tied to low libido or disconnection)
  • GLP-1 stack support (for patients experiencing emotional flatness on semaglutide or tirzepatide)

Sample Protocol Template

DayCompoundDosageNotes
M/W/FNAD+50–100mg SQTitrate based on tolerance; start at lower dose for new users
M/W/FSermorelin300mcg SQ at nightSupports mood via sleep and GH pathways
WeeklyMIC/B6/B121mL IMImproves energy and supports neurotransmitter balance
Daily oralPeptideViteAs directedEnhances mental clarity and stack effectiveness
OptionalL-Carnitine500–1000mg IMFor patients needing mental stamina or motivation

Adjust based on provider guidance, patient tolerance, and response.

Clinical Outcomes to Expect

Patients will typically see:

  • Sharper focus and mental clarity
  • Reduced brain fog and better recall
  • Improved sleep and emotional regulation
  • Increased drive, motivation, and stability
  • Less emotional reactivity and greater stress tolerance

Most patients notice initial improvements within 2–4 weeks, with deeper cognitive gains by week 6–8.

Suggested Protocol Duration

  • Acute support: 6–8 weeks
  • Maintenance: Monthly or cyclical NAD+ and Sermorelin with daily PeptideVite
  • Ideal for layering with GLP-1 or BHRT protocols to preserve mental wellness.

How to Frame This Stack

Use clear, emotionally resonant language:

“This stack helps restore your mental energy, focus, and emotional resilience—especially if stress, aging, or hormones have left you feeling off.”

“You’ll notice better clarity, sharper motivation, and deeper sleep—without stimulants or mood meds.”

→ For more patient phrasing tips: How to Educate Your Patients

Combine With:

  • Perimenopause protocols: For mood and cognitive changes during hormone shifts
  • Post-COVID or fatigue recovery plans: For brain fog and focus loss
  • GLP-1 programs: To offset cognitive dulling during rapid weight loss
  • Biohacking or executive wellness plans: For peak performance clients

ShineRx Support for Implementation

  • Clinical protocol handouts for patients
  • Scripting for patient coordinators and non-clinical staff
  • Dosing schedules and titration support
  • White-labeled symptom tracker templates
  • Fulfillment tracking for refills and follow-ups

→ Build a program around this: Building Bundles & Programs
→ Order confidently via Pharmacy Ordering & Logistics
→ Plan for profitability with Pricing Strategies