Peptide Playbook

Gut Health & Digestive Repair

A Strong Gut Means Stronger Outcomes Everywhere Else

Many clinical challenges—fatigue, inflammation, anxiety, weight resistance—are rooted in gut dysfunction. Whether caused by stress, medications, hormones, or diet, compromised gut health affects immunity, metabolism, and mood.

This stack supports gut lining integrity, inflammation control, and nutrient absorption, helping patients rebuild from the inside out. It’s an ideal companion to aesthetic, GLP-1, or hormone programs—and essential for post-antibiotic or post-COVID recovery.

Ideal Use Cases

Recommend this stack for patients with:

  • Bloating, irregularity, or IBS-like symptoms
  • Poor digestion or nutrient absorption
  • Post-antibiotic or post-GLP-1 gut symptoms
  • Long-COVID or chronic fatigue with suspected gut issues
  • Leaky gut, food sensitivities, or autoimmune triggers
  • History of restrictive dieting or GI inflammation

Best for:

  • Women 35+ in perimenopause/postpartum phases
  • Men with inflammation or digestive fatigue
  • GLP-1 users reporting GI disruption or discomfort
  • Post-infection or chronic immune dysfunction patients

ShineRx Core Compounds for Mood & Focus

CompoundFunctionNotes
GlutathioneReduces gut lining inflammation, supports detox pathwaysIdeal for GI repair, immune reset, and inflammation regulation
NAD+Supports mitochondrial healing and gut-brain communicationEnhances energy and tissue repair post-infection or antibiotic use
PeptideViteReplenishes micronutrients and supports mucosal liningCombats depletion and improves peptide response
MIC/B6/B12Improves methylation, bile flow, and detox metabolismEspecially helpful in slow metabolizers and sluggish digestion
L-CarnitineSupports fat metabolism and GI energy outputOptional in metabolically sluggish or overweight patients

Optional additions:

  • GLP-1 offset protocol (when GI side effects from Semaglutide or Tirzepatide occur)
  • BHRT or cortisol support (when GI symptoms are hormone-linked)

Sample Protocol Template

DayCompoundDosageNotes
M/W/FGlutathione200mg IM or SQCan be paired with NAD+ or MIC/B12 for ease
M/W/FNAD+50–100mg SQEspecially post-COVID or post-antibiotic
WeeklyMIC/B6/B121mL IMSupports bile flow and liver detox pathways
Daily oralPeptideViteAs directedMaintain for 60–90 days for mucosal and absorption support
WeeklyL-Carnitine500–1000mg IMOptional in patients with fatigue or metabolic syndrome

Adjust based on provider guidance, patient tolerance, and response.

Clinical Outcomes to Expect

  • Improved digestion, less bloating/gas
  • More regular and complete bowel movements
  • Reduced food sensitivity reactions
  • Better nutrient absorption and lab normalization
  • Improved skin, mood, and energy via gut-brain axis
  • Better tolerance of GLP-1 or hormonal therapies

Most patients feel initial digestive improvement within 2–3 weeks, with full mucosal repair taking 6–8+ weeks.

Suggested Protocol Duration

  • Initial phase: 6–8 weeks minimum
  • Maintenance: Seasonal 4-week support or post-travel/illness recovery
  • Ideal to offer as part of wellness resets or post-weight loss repair packages

How to Talk About This Stack

“When your gut lining is inflamed, your whole system is affected. This protocol helps repair, rebalance, and strengthen your digestive health from the inside out.”

“Think of this as a reset button for your gut—especially if stress, medications, or rapid weight loss have thrown things off.”

→ See How to Educate Your Patients for full-language scripting and handouts

Best Program Pairings

  • GLP-1 Programs: Add when GI symptoms persist or nutrient depletion is a concern
  • Post-IV Therapy Detox: Great for after heavy metal, alcohol, or medication stress
  • Hormone or BHRT Programs: Supports gut-hormone axis and estrogen metabolism
  • Seasonal Immune Programs: Enhances resilience and gut-lining repair

ShineRx Tools & Resources

  • Patient handouts for gut support protocols
  • Educational visuals on leaky gut, inflammation, and recovery
  • Dosage schedules and stacking templates
  • Pharmacy fulfillment with custom labeling and cold chain protection
  • Staff training modules for GI support scripting

→ Package this into a seasonal bundle in Building Bundles & Programs
→ Streamline ordering via Pharmacy Ordering & Logistics
→ Optimize pricing in Profit Models & Pricing Strategies